Modeling Mendel’s Laws on Inheritance in Computational Biology and Medical Sciences**
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چکیده
The current research article is based on a simple and practical way of employing the computational power of widely available, versatile software MS Excel 2007 to perform interactive computer simulations for undergraduate/graduate students in biology, biochemistry, biophysics, microbiology, and medicine in college and university classroom setting. To accomplish this important motive, we developed the necessary computer algorithm, which used a built-in pseudo-random number generating function in MS Excel 2007, to computer model two basic Mendel’s Laws of heredity for plant and animal species. We performed more than 18,000 computer simulations to investigate the behavior of dominant and recessive genes to verify two basic Mendel’s Laws of heredity. Our simulation work corroborates the experimental observations of Mendel’s research on inheritance in Pisum hybrids. When we compare our results of simulated data with that of experiments done on Drosophila melanogaster, fruit fly extensively being used as a model organism to study genetics and development, an exceedingly good agreement between the simulated and the experimental data has been observed for the F2 generation.
منابع مشابه
Principles of Inheritance: Mendel’s Laws and Genetic Models
It is difficult to overstate the impact of Mendel’s research on the history of genetics; indeed, his research in genetics has been credited as one of the great experimental advances in biology (Fisher, 1965). Prior to the publication of his results on experimental hybridization in plants, the concept of inheritance of physical ‘units’ (later called genes) was accepted, and scientists had report...
متن کاملPrinciples of Inheritance: Mendel’s Laws and Genetic Models
It is difficult to overstate the impact of Mendel’s research on the history of genetics; indeed, his research in genetics has been credited as one of the great experimental advances in biology (Fisher, 1965). Prior to the publication of his results on experimental hybridization in plants, the concept of inheritance of physical ‘units’ (later called genes) was accepted, and scientists had report...
متن کاملPrinciples of Inheritance: Mendel’s Laws and Genetic Models
It is difficult to overstate the impact of Mendel’s research on the history of genetics; indeed, his research in genetics has been credited as one of the great experimental advances in biology (Fisher, 1965). Prior to the publication of his results on experimental hybridization in plants, the concept of inheritance of physical ‘units’ (later called genes) was accepted, and scientists had report...
متن کاملPrinciples of Inheritance: Mendel’s Laws and Genetic Models
It is difficult to overstate the impact of Mendel’s research on the history of genetics; indeed, his research in genetics has been credited as one of the great experimental advances in biology (Fisher, 1965). Prior to the publication of his results on experimental hybridization in plants, the concept of inheritance of physical ‘units’ (later called genes) was accepted, and scientists had report...
متن کاملPrinciples of Inheritance: Mendel’s Laws and Genetic Models
It is difficult to overstate the impact of Mendel’s research on the history of genetics; indeed, his research in genetics has been credited as one of the great experimental advances in biology (Fisher, 1965). Prior to the publication of his results on experimental hybridization in plants, the concept of inheritance of physical ‘units’ (later called genes) was accepted, and scientists had report...
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تاریخ انتشار 2010